Table 2. Intratumoural infiltration with positively stained cells.

	Intraepithelial	Stromal	Intraepithelial/stromal
(a) Infiltration with FOXP3-positive cells (median number of cells per 0.25 mm2)
MSI-H CRC	8.5	181.5	0.05
MSS CRC	3.1	137.1	0.01
P-value	<0.001	0.06	<0.001
(b) Infiltration with CD3-positive cells (median number of cells per 0.25 mm2)
MSI-H CRC	60.8	370.8	0.18
MSS CRC	14.1	320.1	0.05
P-value	<0.001	0.06	<0.001
(c) Infiltration with CD8-positive cells (median number of cells per 0.25 mm2)
MSI-H CRC	32.5	107.4	0.30
MSS CRC	6.3	47.7	0.11
P-value	<0.001	0.009	<0.001

All P-values were computed using the exact Mann–Whitney test.