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. 2008 Dec 15;183(6):1129–1143. doi: 10.1083/jcb.200807020

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© 2008 Harris and Tepass

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Figure 5. — Apical proteins accumulate in an Hrs-positive endocytotic compartment in Cdc42-compromised embryos. (A and B) Wild-type (A and A′) and Cdc42-DN (B and B′) embryos labeled with Crb and the endosome marker Hrs. (C and D) Wild-type (C and C′) and Cdc42-DN (D and D′) embryos labeled for Crb and the early endosome marker Rab5. (E and F) Wild-type (E and E′) and Cdc42-DN (F and F′) embryos labeled for Crb and the early endosome marker Avl. (G and H) Wild-type (G and G′) and Cdc42-DN (H and H′) embryos labeled for Crb and the recycling endosome marker Rab11. (I and J) Embryos expressing the late endosome marker UAS-YFP-Rab7 under the control of da-Gal4 (I and I′) and embryos expressing both UAS-Cdc42-DN and UAS-YFP-Rab7 under the control of da-Gal4 (J and J′) labeled for Crb and GFP. (K and L) Wild-type (K and K′) and Cdc42-DN (L and L′) embryos labeled for Crb and the Golgi marker Lva. (M and N) Wild-type (M and M′) and Cdc42-DN (N and N′) embryos labeled for Crb and the ER marker KDEL. Bars: (A–N) 10 μm; (A′–N′) 5 μm.