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. 2008 Dec 15;183(6):1075–1088. doi: 10.1083/jcb.200806035

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© 2008 Grossmann et al.

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Figure 10. — Model of spatially confined protein turnover. In the presence of low substrate concentrations, specific transporters are concentrated in MCC and protected against internalization (A). After the excess of substrate is supplied (B), the transporters are released from the MCC patches to the surrounding membrane (C) and subjected to endocytosis (D).