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Genomic organization of the miR-133 family. miR-133a-1 and miR-133a-2 have identical sequences, whereas miR-133b differs by 2 nt at the 3′ terminus. Each of the three miR-133 miRNAs is transcribed as a bicistronic transcript with miR-1-2, miR-1-1, or miR-206 as indicated. Genomic distances between the miR coding regions in the mouse genome and expression patterns of each miR cluster are shown.
