Figure 2.
Temperature- and rate- dependence of early afterdepolarization (EAD) activity in M cell preparations pretreated with an IKr blocker, E-4031 (1.0 μmol/L).
A: Transmembrane activity recorded from an M cell preparation at temperatures of 34, 37, and 40°C, recorded at basic cycle lengths (BCL) of 800 and 2000 ms.
B: Plot of temperature- and rate-dependence of EAD incidence in M cell preparations (n=7).