Figure 1. Effect of microinjection of muscimol into the DMH on temperature and locomotor activity to intravenous MDMA.
Changes from baseline over time (minutes) in (A) core temperature and (B) locomotion after microinjecting (t= −5 min) CSF (100nl) or muscimol (80 pmol/100 nl) into the DMH followed by (t = 0 min) intravenous administration of MDMA (7.5 mg/kg) or saline. *significantly different from baseline; ‡significantly different from all other groups at the specified time point. ANOVA and LSD, p < 0.05.