Figure 2. Effect of microinjection of muscimol into the DMH on cardiovascular responses to intravenous MDMA.
Changes over time (minutes) in (A) heart rate and (B) mean arterial pressure after microinjecting into the DMH (t= −5 min) CSF (100nl) or muscimol (80 pmol/100 nl) followed by (t = 0 min) intravenous administration of MDMA (7.5 mg/kg) or saline. *significantly different from baseline; ‡significantly different from all other groups at the specified time point. ANOVA and LSD, p < 0.05.