Table 2. Effects and interactions of all tested parameters including signal-to-noise t-ratios for each case, based on acetone peak amplitude.

(A) Effects for each parameter were calculated using the average acetone peak amplitude found for each of the 16 configurations. Signal-to-noise-ratios were then found by dividing each effect by the calculated standard deviation. (B) Similarly, interactions and their respective t-ratios were also calculated by using the average acetone peak amplitude in accordance with the standard deviation. The critical t value for a statistically significant interaction was t=2.038.

A. Main effects
	Factors of Interest
	A	B	C	D
Main effects	−3.0·10−4	8.0·10−4	4.0·10−4	4.0·10−4
signal-to-noise t-ratio	−3.1088	8.0829	3.997	4.53
significance (|te|>t95)	YES	YES	YES	YES

B. Interaction effects
	Interactions Between Factors
	AB	AC	AD	BC	BD	CD	ABC	ABD	BCD	ABCD
Interaction effects	−1.7·10−5	−3.0·10−3	−5.0·10−5	2.2·10−4	3.7·10−4	6.7·10−5	8.3·10−6	−1.6·10−4	2.6·10−4	−3.3·10−5
signal-to-noise t-ratio	−0.178	−3.375	−0.533	2.309	3.908	0.711	0.089	−1.688	2.754	−0.355
significance (|te|>t95)	NO	YES	NO	YES	YES	NO	NO	YES	YES	NO