Table 3.

The proportion of subjects with cocaine use according to urine drug screens across treatment, with the medication by gender interaction: Z-statistics, and p-values from The GEE model analysis on cocaine

	Female		Male		Gender × NTX Interaction		NTX Main Effect		Gender Main Effect
WEEK	PLAC	NTX	PLAC	NTX	Z	p	Z	p	Z	p
1	0.25	0.29	0.26	0.22	0.58	0.56	−0.80	0.42	−0.32	0.75
7	0.66	0.80	0.69	0.57	2.46	0.01	−3.16	0.002	−1.65	0.10
13	0.66	0.87	0.72	0.52	2.76	0.006	−3.27	0.001	−1.87	0.06

Note: PLAC= placebo; NTX=high dose naltrexone