Table 4.
Association of pelvic osteolytic lesion volume on CT with patient, implant, and radiographic parameters
| Factor | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| Correlation coefficient (r) | p value | Incremental r2 | p value | |
| Patient factors | ||||
| Gender (male = 1, female = 0) | 0.28 | 0.01 | 0.60 | |
| Preoperative diagnosis | ||||
| Osteoarthritis | 0.11 | 0.36 | 0.24 | |
| Osteonecrosis | −0.09 | 0.41 | 0.78 | |
| Developmental hip dysplasia | 0.02 | 0.86 | 0.39 | |
| Posttraumatic arthrosis | −0.08 | 0.50 | 0.33 | |
| Inflammatory arthritis | −0.009 | 0.94 | 0.45 | |
| Age at surgery | −0.14 | 0.22 | 0.19 | |
| Height | 0.09 | 0.44 | 0.65 | |
| Weight | −0.10 | 0.40 | 0.65 | |
| Body mass index | −0.17 | 0.14 | 0.74 | |
| Physician-assessed activity level | ||||
| Heavy | 0.54 | 0.0000003 | 0.05 | 0.00003 | 
| Moderate | −0.20 | 0.08 | 0.40 | |
| Light | −0.22 | 0.06 | 0.37 | |
| Semisedentary | −0.11 | 0.32 | 0.97 | |
| Implant factors | ||||
| Polyethylene liner geometry | ||||
| 4 mm lateralized | −0.003 | 0.98 | 0.05 | |
| Standard | 0.06 | 0.61 | 0.08 | |
| 10° lip | −0.11 | 0.35 | 0.52 | |
| Terminal sterilization | ||||
| Gas plasma | −0.37 | 0.0008 | 0.18 | |
| Gamma-in-air standard dose | 0.48 | 0.00001 | 0.02 | |
| Gamma-barrier standard dose | −0.07 | 0.56 | 0.29 | |
| Gamma-barrier low dose | −0.06 | 0.62 | 0.74 | |
| Shelf storage duration for gamma-in-air liners | 0.38 | 0.0007 | 0.09 | |
| Femoral head material (ceramic = 1, CoCr = 0) | 0.07 | 0.54 | 0.74 | |
| Femoral head diameter | 0.15 | 0.19 | 0.25 | |
| Cup outer diameter | 0.19 | 0.10 | 0.23 | |
| Hole eliminator | ||||
| Plug with positive stop | −0.25 | 0.03 | 0.84 | |
| Plug without positive stop | 0.17 | 0.14 | 0.90 | |
| Not used | 0.14 | 0.21 | 0.67 | |
| Radiographic factors | ||||
| Years between surgery and CT | 0.50 | 0.000003 | 0.94 | |
| Volumetric wear | 0.51 | 0.000002 | 0.02 | 0.002 | 
| Volumetric wear rate | 0.31 | 0.005 | 0.19 | |
| Linear wear | 0.53 | 0.0000006 | 0.84 | |
| Linear wear rate | 0.30 | 0.007 | 0.21 | |
| Number of followup radiographs used to compute wear rate for each hip | 0.42 | 0.0001 | 0.08 | |
| Cup abduction angle | −0.18 | 0.12 | 0.45 | |
| Depth of acetabular seating | 0.11 | 0.34 | 0.33 | |
| Days between radiographs and CT | −0.21 | 0.06 | 0.59 | |
| Femoral lysis area on radiograph | 0.16 | 0.15 | 0.74 | |
| Pelvic lysis area on radiograph | 0.89 | 4 × 10−18 | 0.80 | 4 × 10−18 |