Table 4.

Teeth number, periodontal disease and risk of leukemia, non-Hodgkin lymphoma and multiple myeloma in the HPFS cohort (1986–2004, 714,294 person-years)

Cancer site	Teeth number			Periodontal disease
	25–32	17–24	0–16	No	Yes
Non-Hodgkin lymphoma	430	60	34	403	121
HR (95% CI)*	1.0 (referent)	0.76 (0.58–1.00)	0.80 (0.56–1.16)	1.0 (referent)	1.31 (1.06–1.62)
Leukemia	195	37	18	194	56
HR (95% CI)*	1.0 (referent)	1.05 (0.73–1.50)	1.02 (0.62–1.70)	1.0 (referent)	1.34 (0.98–1.82)
Multiple myeloma	101	25	15	106	35
HR (95% CI)*	1.0 (referent)	1.28 (0.81–2.01)	1.42 (0.80–2.53)	1.0 (referent)	1.30 (0.88–1.94)

^*Hazard ratios (HR) and 95% confidence intervals (CI) controlling for age (continuous), race (White, Asian, Black), physical activity (quintiles), history of diabetes (yes/no), alcohol (quartiles), body mass index (<22, 22–24,9, 25–29.9, 30+), geographic location (south, west, northeast, midwest), height (quintiles), calcium intake (quintiles), total caloric intake (quintiles), red meat intake (quintiles), fruit and vegetable intake (quintiles), vitamin D score (deciles), smoking history (never, past quit ≤10 yrs, past quit >10 yrs, current 1–14 cig/d, 15–24 cig/d, 25+ cig/d) and pack-years (continuous).