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. Author manuscript; available in PMC: 2008 Dec 12.
Published in final edited form as: Circulation. 2008 Jun 9;117(24):3070–3078. doi: 10.1161/CIRCULATIONAHA.107.763870

Figure 3.

Figure 3

Severe pressure stress induces cardiomyocyte autophagy. A, Representative electron micrograph revealing a multilamellar autophagosome in basal septum of LV 48 hours after sTAB (scale bar=500 nm). B, Anti-LC3 immunofluorescence reveals redistribution of LC3 into punctate dots, indicative of autophagosome accumulation (scale bar=10 μm). C, Representative immunoblot demonstrating that severe pressure stress triggers significant LC3 processing.