Table 4.

Studies evaluating monounsaturated fat intake and endometrial cancer risk

Reference	Country	Age	Cases/ Controls or total cohort	Exposure evaluated	Contrast	RR/OR	95% confidence interval	P for trend	Covariates Considered*
									A	B	E	S	H	R
Cohort studies
Jain et al., 2000 [26]†	Canada	40-59	221/3,697	Oleic acid, g/day	>39.2 vs. <32.5 g	0.79	0.54, 1.17		1	1	1	1	1	2
Population-based case-control studies
Goodman et al., 1997 [29]	United States	18-84	332/511	Monounsaturated fat, g/day	>32.5 vs. <15.7 g	2.5		0.03	(1)	1	1		1	1
Jain et al., 2000 [31]	Canada	30-79	552/562	Monounsaturated fat, g/day	>26.4 vs. <17.4 g	1.08	0.76, 1.53	0.63	1	1	1	1	1	2
McCann et al., 2000 [32]	United States	40-85	232/639	Monounsaturated fat, g/day	>28 vs. <16 g	0.9	0.4, 1.8	0.08	1	1	1	1	1	3
Potischman et al., 1993 [23]	United States	20-74	399/296	Oleic acid, g/day	>25 vs. <13 g	2.2	1.2, 4		1	1	‡	1	1	1
Littman et al., 2001 [25]	United States	45-74	679/944	Oleic acid, g//1000 kcal/day	>35.9 vs. <14.4 g	1.4	1, 2	0.01	1	1	1	1	1
Hospital-based case-control studies
Tzonou et al., 1996 [34]	Greece		145/298	Monounsaturated fat, g/day	Per 15 g	0.76	0.56, 1.03		1	1	1	1	1	5
Salazar-Martinez et al., 2005 [33]	Mexico	18-81	85/629	Monounsaturated fat, g/day	>19 vs. <12 g	0.98	0.41, 2.43	0.79	1	1	1			1

^*Adjustment columns: A = Age; B = BMI/weight; E = Total Energy; S = Smoking; H = HRT/ERT use; R = Reproductive factors; (1): matched on age. Numbers in columns refer to the number of covariates adjusted for under that grouping.

^†Case-cohort design.

^‡Adjusted for carbohydrate calories.

Abbreviations: OR: odds ratio, RR: relative risk.