Table 6.

Studies evaluating cholesterol intake and endometrial cancer risk

Reference	Country	Age	Cases/ Controls or total cohort	Exposure evaluated	Contrast	RR/ OR	95% confidence interval	P for trend	Covariates Considered*
									A	B	E	S	H	R
Population-based case-control studies
Potischman et al., 1993 [23]	United States	20-74	399/296	Cholesterol, mg/day	>245 vs. <123 mg	2	1.2, 3.3		1	1	†	1	1	1
Goodman et al., 1997 [29]	United States	18-84	332/511	Cholesterol, mg/day	>302 vs. <132 mg	2.2		0.02	(1)	1	1		1	1
McCann et al., 2000 [32]	United States	40-85	232/639	Cholesterol, mg/day	>427 vs. ≤239 mg	0.7	0.4, 1.4	0.03	1	1	1	1	1	3
Littman et al., 2001 [25]	United States	45-74	679/944	Cholesterol, mg/day	>341.5 vs. <122.3 mg	1.3	0.85, 2.1	0.15	1	1	1	1	1
Hospital-based case-control studies
Barbone et al., 1993 [35]	United States		102/203	Cholesterol, mg/day	>293.6 vs. <218.9 mg	1.6	0.8, 2.9	0.23	1	1	1	1	1	3
Tzonou et al., 1996 [34]	Greece		145/298	Cholesterol, mg/day	Per 70 mg	1.09	0.76, 1.57		1	1	1	1	1	5
Salazar-Martinez et al., 2005 [33]	Mexico	18-81	85/629	Cholesterol, mg/day	>186 vs. <126 mg	0.81	0.37, 1.76	0.65	1	1	1			1

^*Adjustment columns: A = Age; B = BMI/weight; E = Total Energy; S = Smoking; H = HRT/ERT use; R = Reproductive factors; (1): matched on age. Numbers in columns refer to the number of covariates adjusted for under that grouping.

^†Adjusted for carbohydrate calories.

Abbreviations: OR: odds ratio, RR: relative risk.