Table 9.
Calculated Rotamer Populations for Tyr and Trp of Analogous Peptides in DMSO-d6.
Rotamer | Compound 1a | DPDPEb | DPDPEc | CCK-7(ns)d | |
---|---|---|---|---|---|
Gauche (−)e | 42 | 39 | 27.0(73.0) | 25 | |
Tyr | Transe | 41 | 60 | 73.0(27.0) | 58 |
Gauche (+) | 17 | 3 | 0 | 17 | |
Gauche (−)e | 65 | 69 | 73.0(27.0) | 20 | |
Trp/Phe | Transe | 23 | 17 | 27.0(73.0) | 63 |
Gauche (+) | 11 | 14 | 0 | 17 |