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. Author manuscript; available in PMC: 2008 Dec 12.
Published in final edited form as: Stroke. 2007 Apr 5;38(5):1578–1584. doi: 10.1161/STROKEAHA.106.473967

Figure 1.

Figure 1

Experimental timeline. Chloralose-anesthetized animals underwent 10 minutes of cardiac arrest followed by 2 hours of reperfusion under hyperoxic (100% O2) or normoxic (21% to 30% O2) conditions for the first hour. [1-13C]glucose (0.2 mg/kg) was infused from 30 to 60 minutes of reperfusion. During the second hour of reperfusion, the ventilator settings were adjusted to maintain arterial pO2 at >80 and <120 mm Hg. At the end of the second hour, brains were removed and immediately immersed in liquid N2 (see Methods for details).