Skip to main content
. Author manuscript; available in PMC: 2008 Dec 12.
Published in final edited form as: Stroke. 2007 Apr 5;38(5):1578–1584. doi: 10.1161/STROKEAHA.106.473967

TABLE 2. Hippocampal Amino Acid Concentrations (nmol/mg protein) After Cardiac Arrest and 2-Hour Reperfusion.

Nonischemic Hyperoxic Normoxic
Aspartate 111.9±18.3 101.1±13.2 96.2±24.0
Glutamate 670.9±90.3 785.2±86.4 683.3±73.6
Glutamine 171.8±70.7 334.2±73.9 235.7±67.5
GABA 75.2±13.0 127.9±21.3 117.1±10.9
Alanine 38.5±6.7 84.4±16.9* 77.1±7.5

Amino acids were determined by HPLC on extracts of frozen hippocampi from sham-operated, nonischemic animals and from animals after 10 minutes of cardiac arrest and 2-hour reperfusion using hyperoxic or normoxic resuscitation (Methods). Values are mean±SE for n=7 nonischemic, 7 hyperoxic, and 6 normoxic animals.

*

Significantly different from nonischemic controls (P<0.05).