Table 1.
Wall shear rate in venules and arterioles of control (n = 10) and colitic (n = 9) WT mice, non-colitic EPCR-TgN mice (n = 6), colitic EPCR-TgN mice (n = 12), control (n = 12) and colitic (n= 11) WT mice treated with APC, and control (n = 10) and colitic (n = 10) WT mice treated with an APC blocking mAb.
| Wall Shear Rate (s−1) | ||
|---|---|---|
| Venules | Arterioles | |
| Control WT | 644.35 ± 27.83 | 923.80 ± 54.94 |
| Colitic WT * | 633.23 ± 49.29 | 921.77 ± 42.56 |
| Non-colitic EPCR-TgN | 645.53 ± 26.58 | 1157.47±170.84 |
| Colitic EPCR-TgN | 743.22 ± 47.66 | 858.85 ± 60.20 |
| Control WT + murine APC | 657.13 ± 41.21 | 968.44 ± 80.53 |
| Colitic WT + murine APC | 833.50 ± 149.13 | 914.42 ± 132.62 |
| Control WT + APC mAb | 712.98 ± 65.85 | 917.72 ± 97.73 |
| Colitic WT + APC mAb | 845.47 ± 120.02 | 1088.38 ± 144.32 |
Colitic mice received 3 % DSS, while controls received water only.