Figure 2. NPY structure, genotyped SNPs, and LD between SNPs.

NPY gene structure is displayed diagrammatically (top), with exons symbolized as cylinders, and sites of translation initiation (ATG) and termination (TGA) indicated. Genotyped SNPs are noted with arrows and color-coded: coding-nonsynonymous (red); coding-synonymous (green); intronic (blue); mRNA-untranslated region (lavender); 5′ and 3′ gene-flanking region (black). The bottom panel constitutes a LD graphic with R² values (n×10²) between SNPs; darker squares signify higher degrees of LD. SNPs genotyped as part of this study are highlighted in yellow.