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Normalized melting temperature curves of the non- and Se-modified DNA duplexes. The Se-DNA duplex: 5′-CGTACCTACAGTT-SeG-T-3′ and 5′-ACAACTGTAGGTACG-3′ (Open circle, Tm = 51.1°C); the corresponding native DNA duplex: (filled diamond, 55.0°C).
