Figure 5.
Intragraft mRNA levels of inflammatory mediators. mRNA for the proinflammatory cytokines IL-6, IL-1β and TNF-α, the stress-induced molecules iNOS and COX-2 and the adhesion molecule ICAM-1 were rapidly upregulated within 2 hours after reperfusion in control animals. 5% CO-UW significantly reduced expression of these inflammation-related molecules. (* p<0.05 vs. control UW group)