Table 2.
Mean percentage of human blood DC subsets in PBMC and relative proportion of DC subsets in T1D versus control subjects.
| LS Means (%) |
p value |
|||
|---|---|---|---|---|
| NC | T1D | NC-T1D | Age* | |
| pDC/PBMC | 0.188 | 0.127 | 6.0×10-5 | 0.0007 |
| mDC1/PBMC | 0.225 | 0.214 | 0.83 | 0.111 |
| mDC2/PBMC | 0.013 | 0.013 | 0.99 | 0.333 |
| DC/PBMC | 0.426 | 0.353 | 0.028 | 0.006 |
| pDC/DC | 44.3 | 35.7 | 0.00018 | 0.031 |
| mDC1/DC | 52.7 | 60.7 | 0.0002 | 0.067 |
| mDC2/DC | 3.1 | 3.7 | 0.098 | 0.007 |
| pDC/mDC1 | 0.69 | 0.52 | 0.0006 | 0.03 |
NC = normal controls. LS means are within-group means appropriately adjusted for the other effects in the model (subject age in this case). P values for age are derived from regression analysis for subject age in all subjects (T1D + NC). P-values under “Age” denote p value after ANCOVA.