TABLE 2.

Plasma HDL concentrations in B6, 129, F₁, and F₂, progeny

	Chow diet		Atherogenic diet
	Female	Male	Female	Male
B6 (n = 10)	56 ± 7	70 ± 7	64 ± 5	95 ± 6
129 (n = 10)	93 ± 11a	128 ± 7a	167 ± 12a	185 ± 14a
F1 (n = 10)	86 ± 7b	107 ± 7c	110 ± 9c	127 ± 10c
F2 (n = 528)d	83 ± 21	99 ± 20	130 ± 40	160 ± 50

Data are presented as the means ± SD.

^aP < 0.01 vs. B6.

^bP < 0.01 from B6 but not significantly different from 129.

^cP < 0.01 vs. B6 and 129.

^dBecause it is the distribution, not the mean, among the F₂ population that is most important for detecting genetic linkage to a phenotype, we did not test for significant differences between F₂ progeny and either the parental strains or F1 progeny.