TABLE 2.
Doubling times (T in hours) were calculated by fitting the data from a parasite growth curve as quantified using Giemsa-stained blood smears counted in triplicate to the equation y = Noekx, where No is the initial population and k is the growth constant. The growth constant was used to determine doubling time. The error indicates S.E. of the parameters used for the curve fit.
|
Hypoxanthine
|
||
|---|---|---|
| 10 μm | 100 μm | |
| Parasite line | T (h) | T (h) |
| hrpII integrant | 9.1 ± 0.4 | 7.0 ± 0.4 |
| Δpfpnp 1 | 26 ± 4 | 7.6 ± 0.4 |
| Δpfpnp 2 | 22 ± 2 | 7.4 ± 0.4 |