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. Author manuscript; available in PMC: 2008 Dec 15.
Published in final edited form as: Oncogene. 2008 Jun 30;27(47):6120–6130. doi: 10.1038/onc.2008.207

Figure 4. Effects of HER2 overexpression on invasive properties of Aldelfuor-positive and -negative populations of breast cancer cell lines.

Figure 4

Aldefluor-positive populations from Sum159-DsRed, SUM159-HER2 (A), MCF7-DsRed or MCF7-HER2 cells (B) showed significantly higher invasiveness compared to Aldefluor-negative populations. Furthermore, HER2 overexpression resulted in a 5 to 6-fold increase in the invasive potential of Aldefluor-positive cells.