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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: Neuropharmacology. 2008 Jul 30;55(7):1183–1190. doi: 10.1016/j.neuropharm.2008.07.026

Figure 3.

Figure 3

Effects of cumulative doses of Δ9-THC on locomotor counts (left panels), change in rectal temperature (middle panels), and immobility in the bar test (right panels) following sub-chronic treatment with saline, haloperidol, and clozapine in adult (top panels) and adolescent (bottom panels) male rats. Points above VEH show effects of 1:1:18 (ethanol:emulphor:saline) vehicle for rats in each treatment group. Each value represents the mean ± SEM of data from adolescent rats (n=7, saline; n=9, haloperidol; n=7, clozapine) and adult rats (n=10 all treatments). h$ and c$ indicate significant main effect of Δ9-THC dose (p<0.05), as compared to vehicle (at left in each panel), in haloperidol- and clozapine-treated rats, respectively. @ (in symbol legend on figure) indicates a significant main effect of haloperidol treatment (p<0.05), as compared to saline treatment, on change in rectal temperature. h* indicates significant haloperidol treatment X Δ9-THC dose interaction and post hoc determination of difference between haloperidol vs. saline treatment at indicated Δ9-THC dose (p<0.05).