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SINVs expressing Mx or Rpr cause DNA fragmentation indicative of apoptosis. (A and B) C6/36 cells were mock-infected or infected with the indicated SINVs (m.o.i. = 1). At 24 hpi, cells were lysed and DNA was analyzed by agarose gel electrophoresis and ethidium bromide staining. (C) C6/36 cells were infected with the indicated SINVs (m.o.i. = 0.01) for 48 h, stained with Hoechst 33258, and photographed (magnification, 400X).
