Table 1.

Primary and secondary engraftment of NOD/SCID mice with clonotypic B cells isolated from the peripheral blood of multiple myeloma patients

Patient	Primary engraftment				Secondary engraftment
	Cells injected (×106)	Time (wk)*	% CD138 †	% CD19 †	Cells injected (×103)	Time (wk)*	% CD138 †	% CD19 †
1	1.2	20	8.7	0.02	10.8	22	12.1	0.06
2	1	20	4.3	0.01	Nd	Nd	Nd	Nd
3	4.3	16	15	0.06	100	26	8.9	0.05
4	0.8	25	6.6	0.02	14.1	26	7.2	0.05

^*Time after transplantation to the development of signs of multiple myeloma.

^†Frequency of Ig light chain–restricted cells within mouse bone marrow; nd, not done.