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. Author manuscript; available in PMC: 2009 Sep 10.

Published in final edited form as: J Control Release. 2008 Apr 24;130(2):129–138. doi: 10.1016/j.jconrel.2008.04.014

Effect of linear PEI complexed with 25 micrograms of pDNA at different N/P ratios on gene expression in Balb/C. (a) Quantification of the signal produced in Balb/c mice after IP injection of each formulation. Values shown are mean ± standard deviation (n=3). (b)–(f) Luciferase expression in Balb/C mice measured by IVIS. (b), (c), (d), (e) and (f) represent 24 hours, 48 hours, 72 hours, 7 days and 14 days after injection. The number of photons is depicted in a color image superimposed on a video image of the animal. Each mouse presented in the figure is representative of at least three mice in each experiment.

Effect of linear PEI complexed with 25 micrograms of pDNA at different N/P ratios on gene expression in Balb/C. (a) Quantification of the signal produced in Balb/c mice after IP injection of each formulation. Values shown are mean ± standard deviation (n=3). (b)–(f) Luciferase expression in Balb/C mice measured by IVIS. (b), (c), (d), (e) and (f) represent 24 hours, 48 hours, 72 hours, 7 days and 14 days after injection. The number of photons is depicted in a color image superimposed on a video image of the animal. Each mouse presented in the figure is representative of at least three mice in each experiment.