MI over time for 10 replicates where mutation is removed (at iteration=0) and then returned (at iteration 10 000) at the end of a single simulation run. Panels represent runs with particular parameter values. (a) p=0.95, =2, population mean MI at iteration 0=0.4904. (b) p=0.75, =2, population mean MI at iteration 0=0.3063. (c) p=0.5, =0.5, population mean MI at iteration 0=0.3560. (d) p=0.5, =2, population mean MI at iteration 0=0.1879. (e) p=0, =0.5, population mean MI at iteration 0=0.0809. (f) p=0, =2, population mean MI at iteration 0=0.0104.