Table 5. Reported intracellular concentrations of the activated (tri-phosphate) form of the nucleoside and nucleotide analogs, measured in peripheral blood mononuclear cells in patients.
Activated Analog | Intracellular Concentration Range (mM) |
3TC-TP | 35.4–51.2 |
FTC(−)-TP | 0.40–4.50 |
AZT-TP | 0.84–1.2 |
ABC-TP | 0.04–0.75 |
TDF-TP | 0.27–0.39 |
ddA-TP | 0.013–0.078 |
d4T-TP | 0.016–0.082 |
Acyclovir-TP | Not available |
ddC-TP | Not available |