Table 2. Summary of densitometry analyses of normalized protein levels of HIF-1α, VEGFR-1, HIF-2α, VEGFR-2, and VEGF obtained by immunoblotting using lysates isolated from aortic banded and sham operated animals exposed to either normoxia or hypoxia.
SHAM NORM | BAND NORM | SHAM HYPOX | BAND HYPOX | |
HIF-1α | + | +++ | +++ | +++ |
VEGFR-1 | +/− | +/− | + | ++ |
VEGFR-2 | + | + | +++ | + |
HIF-2α | − | − | ++ | +/− |
VEGF | +++ | +++ | +++ | +++ |
Results are based upon 3–5 hearts/group.