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. Author manuscript; available in PMC: 2008 Dec 16.
Published in final edited form as: Angew Chem Int Ed Engl. 2008;47(31):5700–5702. doi: 10.1002/anie.200801801

Scheme 1.

Scheme 1

The role of CrtM in staphyloxanthin biosynthesis. The S. aureus squalene cyclase CrtM catalyzes the formation of dehydrosqualene from two molecules of farnesyl diphosphate. Dehydrosqualene is subsequently converted to staphyloxanthin.