Figure 2.
Time course of brain IL-1 production following E.coli challenge. Rats were injected i.p. with saline or 2.5×10^8 CFU E.coli and sacrificed 2, 4, 6, or 8 h later for measurement of hypothalamic and hippocampal IL-1 by ELISA. Bars represent group averages +/− SEM (n=4/group). * represents p < 0.05 compared to saline-injected controls.