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. Author manuscript; available in PMC: 2009 Oct 1.
Published in final edited form as: Brain Behav Immun. 2008 May 12;22(7):1078–1086. doi: 10.1016/j.bbi.2008.03.007

Figure 8.

Figure 8

Effect of peripherally administered nadolol on circulating proinflammatory cytokine production following peripheral E.coli challenge. Rats were injected i.p. with either saline (Sal) or nadolol (Nad; β-antagonist) immediately prior to challenge with i.p. saline or E.coli. Animals were sacrificed 6 h later for measurement of plasma A) IL-1, B) IL-6, and C) TNF-α. Bars represent group averages +/− SEM (n=6–8/group). * represents p < 0.05 compared to saline-injected controls. # represents p < 0.05 compared to E.coli group receiving i.p. saline.