Table 3.

Effect of Three Experimental Interventions on Daylong Integrated Plasma Glucose, Insulin, Free Fatty Acid, and Triglyceride Responses to Test Meals

Variable (Area-under -the curve)	Fenofibrate (n=12)				Rosiglitazone (n=12)				Calorie-Restricted Diet (n=12)
	Before	After	Change	p	Before	After	Change	p	Before	After	Change	p
Glucose (mg/dl.8hr)	838 ± 103	845 ± 108	1%	0.70	890 ± 101	836 ± 85	−6%	0.02	899 ± 129	850 ± 126	−6%	0.02
Insulin (µU/ml.8hr)	499 ± 164	501 ± 163	0.4%	0.88	520 ± 379	301 ± 154	−42%	<0.001	540 ± 219	419 ± 179	−22%	<0.001
Free Fatty Acids (mmol/l.8hr)	1455 ± 334	1608 ± 428	9.5%	0.18	1793 ± 511	1221 ± 393	−32%	0.001	1489 ± 362	1402 ± 334	−6%	0.34
Triglycerides (mg/dl.8hr)	2120 ± 887	1492 ± 473	−30%	0.01	2067 ± 787	2034 ± 639	−2%	0.94	1796 ± 859	1565 ± 494	−13%	0.36

Within each experimental group, before and after means were compared by Student’s paired t-test