Figure 5. Pharmacological antagonism of PCP treatment on PN7 effects on NR1 and NR2B in the frontal cortex.
Quantitative analysis reveals that antipsychotics pretreatment has no effect on PCP treatment on PN7-induced up-regulation of NR1 or NR2B protein levels in the frontal cortex 24 hours following PCP (10 mg/kg, N=5–15/treatment). *p<0.05 vs. SAL NR1 (one-way ANOVA with Bonferroni's post hoc test) ^p<0.05 vs. SAL NR2B (one way ANOVA with Bonferroni’s post hoc test).