TABLE 1.
Demographic and clinical characteristics of the study groups
| Group | |||
|---|---|---|---|
| Variable | TAA (n = 28) | TAD (n = 60) | Control (n = 111) |
| Male sex | 21 (75%) | 46 (77%) | 63 (57%) |
| Mean age ± SD (y) | 67.2 ± 10.0 | 59.9 ± 12.6 | 51.7 ± 11.0 |
| Age range (y) | 42-81 | 22-81 | 17-80 |
| Smoking history | |||
| None | 5(18%) | 22 (37%) | * |
| Current | 10(36%) | 11 (18%) | * |
| Past | 13(46%) | 27 (45%) | * |
| Previous cardiac-aortic surgery | 7 (25%) | 29 (48%) | * |
| Coronary artery bypass | 4 | 7 | 0 |
| Aortic valve replacement | 0 | 7 | * |
| Ascending aorta | 1 | 19 | 0 |
| Aortic arch | 1 | 6 | * |
| Descending thoracic aorta | 1 | 2 | * |
| Abdominal aorta | 2 | 1 | * |
| Thoracoabdominal aorta | 2 | 0 | * |
| Taking lipid-lowering medication | 19(68%) | 23 (38%) | * |
| Family history of aneurysm | 4 (14%) | 4 (7%) | * |
| Family history of dissection | 0 | 3 (5%) | * |
| Bicuspid aortic valve | 0 | 1 (2%) | * |
| Arteritis | 0 | 1 (2%) | * |
| Rupture | 1 (4%) | 1 (2%) | NA |
| Location of degenerative aneurysm(s) | |||
| Aortic root | 3 (11%) | 0 | NA |
| Ascending aorta | 10 (36%) | 2 (3%)† | NA |
| Transverse aortic arch | 6 (21%) | 0 | NA |
| Descending thoracic aorta | 1 (4%) | 0 | NA |
| Thoracoabdominal aorta | 17 (61%) | 1 (2%)† | NA |
| Acuity of dissection | |||
| Acute | 2 (7%)† | 13 (22%) | NA |
| Chronic | 1 (4%)† | 47 (78%) | NA |
| Extent of dissection | |||
| DeBakey type 1 | 0 | 25 (42%) | NA |
| DeBakey type II | 1 (4%)† | 11 (18%) | NA |
| DeBakey type III | 2 (7%)† | 24 (40%) | NA |
| Mean no. of segments involved ± SD ‡ | 2.6 ± 1.4 | 2.9 ± 1.3 | NA |
| Mean maximum aortic diameter ± SD (cm) | 6.2 ± 1.3 | 6.1 ± 1.4 | * |
| Range of maximum aortic diameter (cm) | 4.0-9.0 | 3.6-10.0 | * |
TAA, Thoracic aortic aneurysm; TAD, thoracic aortic dissection; SD, standard deviation; NA, not applicable.
Not obtained.
Three patients had both thoracic aortic aneurysm and thoracic aortic dissection and are included in both groups.
Based on involvement of up to 5 aortic segments: ascending, transverse arch, descending thoracic, suprarenal abdominal, and infrarenal abdominal.