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. Author manuscript; available in PMC: 2009 Feb 14.
Published in final edited form as: Cell Host Microbe. 2008 Aug 14;4(2):134–146. doi: 10.1016/j.chom.2008.06.008

Fig. 6. Effect of readthrough transcription on histone modifications at the HIV-1 LTR.

Fig. 6

Histone modifications in the vicinity of the integrated provirus were analyzed by ChIP assays using antibodies to H3K9,14Ac, H3K27me3 and H3K36me3 for precipitation followed by amplification of the region (+437 to + 543) downstream of the transcriptional start site of HIV-1. (a)–(c) Differences between the Readthrough (−) Convergent and the Readthrough (+) Convergent cells in levels of H3K9,14Ac, H3K27me3 and H3K36me3, respectively. (d)–(f) Differences between the Readthrough (−) Same and the Readthrough (+) Same cells in H3K9,14Ac, H3K27me3 and H3K36me3, respectively. The white bars refer to the Readthrough (−) cells, and the black bars to the Readthrough (+) cells.