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. 1960 Aug;33(1):1–14.

Hepatic Liposis and Myocardial Damage in Mice Fed Choline-Deficient or Choline-Supplemented Diets **

W Lane Williams
PMCID: PMC2604214  PMID: 13785529

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10-2Figs. 5-8
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10-3Figs. 9-12
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10-4Figs. 13-16
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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BEST C. H., HARTROFT W. S. Nutrition, renal lesions and hypertension. Fed Proc. 1949 Sep;8(3):610-7, illust. [PubMed] [Google Scholar]
  2. BEST C. H., LEWIS L. A., WILGRAM G. F. Effect of choline and cholesterol on lipoprotein patterns of rats. Circ Res. 1957 Jan;5(1):111–114. doi: 10.1161/01.res.5.1.111. [DOI] [PubMed] [Google Scholar]
  3. BUCKLEY G. F., HARTROFT W. S. Pathology of choline deficiency in the mouse; observations with special reference to liver. AMA Arch Pathol. 1955 Feb;59(2):185–197. [PubMed] [Google Scholar]
  4. HARTROFT W. S. Accumulation of fat in liver cells and in lipodiastaemata preceding experimental dietary cirrhosis. Anat Rec. 1950 Jan;106(1):61–87. doi: 10.1002/ar.1091060107. [DOI] [PubMed] [Google Scholar]
  5. HARTROFT W. S. Effects of various types of lipids in experimental hypolipotropic diets. Fed Proc. 1955 Jun;14(2):655–660. [PubMed] [Google Scholar]
  6. HARTROFT W. S., RIDOUT J. H., SELLERS E. A., BEST C. H. Atheromatous changes in aorta, carotid and coronary arteries of choline-deficient rats. Proc Soc Exp Biol Med. 1952 Nov;81(2):384–393. doi: 10.3181/00379727-81-19885. [DOI] [PubMed] [Google Scholar]
  7. HIGHMAN B., DAFT F. S. Calcified lesions in C3H mice given purified low-protein diets; tissues involved: heart, skeletal muscles, arteries, and lungs. AMA Arch Pathol. 1951 Sep;52(3):221–229. [PubMed] [Google Scholar]
  8. JONES R. J., WISSLER R. W., HUFFMAN S. Certain dietary effects on the serum cholesterol and atherogenesis in the rat. AMA Arch Pathol. 1957 Jun;63(6):593–601. [PubMed] [Google Scholar]
  9. MANN G. V., ANDRUS S. B., McNALLY A., STARE F. J. Experimental atherosclerosis in Cebus monkeys. J Exp Med. 1953 Sep;98(3):195–218. doi: 10.1084/jem.98.3.195. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. MEADER R. D., WILLIAMS W. L. Choline deficiency in the mouse. Am J Anat. 1957 Mar;100(2):167–203. doi: 10.1002/aja.1001000202. [DOI] [PubMed] [Google Scholar]
  11. STAMLER J., BOLENE C., HARRIS R., KATZ L. N. Effect of choline and inositol on plasma and tissue lipids and atherosclerosis in the cholesterol-fed chick. Circulation. 1950 Nov;2(5):714–721. doi: 10.1161/01.cir.2.5.714. [DOI] [PubMed] [Google Scholar]
  12. THOMAS W. A., HARTROFT W. S. Myocardial infarction in rats fed diets containing high fat, cholesterol, thiouracil, and sodium cholate. Circulation. 1959 Jan;19(1):65–72. doi: 10.1161/01.cir.19.1.65. [DOI] [PubMed] [Google Scholar]
  13. WILGRAM G. F. A survey of experimental arteriopathies in the rat. AMA Arch Pathol. 1957 Dec;64(6):629–632. [PubMed] [Google Scholar]
  14. WILGRAM G. F., BEST C. H., BLUMENSTEIN J. Effect of growth hormone and testosterone on induction of cardiovascular changes in choline-deficient rats. Proc Soc Exp Biol Med. 1956 Apr;91(4):620–622. doi: 10.3181/00379727-91-22351. [DOI] [PubMed] [Google Scholar]
  15. WILGRAM G. F., HARTROFT W. S., BEST C. H. Abnormal lipid in coronary arteries and aortic sclerosis in young rats fed a choline-deficient diet. Science. 1954 Jun 11;119(3102):842–843. doi: 10.1126/science.119.3102.842. [DOI] [PubMed] [Google Scholar]
  16. WILGRAM G. F., HARTROFT W. S., BEST C. H. Dietary choline and the maintenance of the cardiovascular system in rats. Br Med J. 1954 Jul 3;2(4878):1–5. doi: 10.1136/bmj.2.4878.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. WILGRAM G. F., HARTROFT W. S. Pathogenesis of fatty and sclerotic lesions in the cardiovascular system of choline-deficient rats. Br J Exp Pathol. 1955 Jun;36(3):298–305. [PMC free article] [PubMed] [Google Scholar]
  18. WILGRAM G. F., LEWIS L. A., BLUMENSTEIN J. Lipoproteins in choline deficiency. Circ Res. 1955 Nov;3(6):549–552. doi: 10.1161/01.res.3.6.549. [DOI] [PubMed] [Google Scholar]
  19. WILLIAMS W. L., ARONSOHN R. B. Cardiac and hepatic lesions in mice fed yeast-protein diets. I. Diets containing British bakers yeast. Yale J Biol Med. 1956 Apr;28(5):515–524. [PMC free article] [PubMed] [Google Scholar]
  20. WILLIAMS W. L., CARDLE J. B., MEADER R. D. The nature of dietary fat and the pattern of hepatic liposis in choline-deficient mice. Yale J Biol Med. 1959 Apr;31(5):263–270. [PMC free article] [PubMed] [Google Scholar]
  21. WILLIAMS W. L. Cytoplasmic changes in hepatic parenchyma of mice during starvation and carbon tetrachloride-induced injury. Anat Rec. 1951 Dec;111(4):629–651. doi: 10.1002/ar.1091110404. [DOI] [PubMed] [Google Scholar]
  22. WILLIAMS W. L., DAVIS R. L. Effects of cortisone and vitamin B12 on starved mice. Anat Rec. 1959 May;134:7–23. doi: 10.1002/ar.1091340103. [DOI] [PubMed] [Google Scholar]
  23. WILLIAMS W. L., FRANTZ M. Histological technics in the study of vitally stained normal and damaged cells. Anat Rec. 1948 Apr;100(4):547–559. doi: 10.1002/ar.1091000405. [DOI] [PubMed] [Google Scholar]
  24. WISSLER R. W., EILERT M. L., SCHROEDER M. A., COHEN L. Production of lipomatous and atheromatous arterial lesions in the albino rat. AMA Arch Pathol. 1954 Apr;57(4):333–351. [PubMed] [Google Scholar]

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