TABLE 1.
Preliminary guideline for the assignment of Canadian epidemic types using spa typing (see also Table S1 <www.pulsus.com>). spa types indicated in bold were identified as Canadian methicillin-resistant Staphylococcus aureus (CMRSA) pulsed-field gel electrophoresis (PFGE) epidemic types from the 300 isolates used for validation from the 2007 Canadian Nosocomial Infection Surveillance Program and were subsequently added to the table (see also Table S2 <www.pulsus.com>)
| Epidemic type | Ridom spa type | Number of isolates observed | Unique PFGE types | Ridom repeat succession | Kreiswirth repeat succession |
|---|---|---|---|---|---|
| CMRSA1 (n=183) | t004 | 123 | 85 | r09r02r16r13r13r17r34r16r34 | A2AKEEMBKB |
| t015 | 2 | 2 | r08r16r02r16r34r13r17r34r16r34 | XKAKBEMBKB | |
| t026 | 3 | 2 | r08r16r34 | XKB | |
| t040 | 1 | 1 | r09r02r16r13r17r34r16r34 | A2AKEMBKB | |
| t050 | 1 | 1 | r08r16r02r16r34r34r17r34r16r34 | XKAKBBMBKB | |
| t061 | 5 | 4 | r09r02r16r13r34r17r34r16r34 | A2AKEBMBKB | |
| t065 | 8 | 7 | r09r02r16r34r13r17r34r16r34 | A2AKBEMBKB | |
| t130 | 3 | 2 | r09r34r13r17r34r16r34 | A2BEMBKB | |
| t132 | 1 | 1 | r09r34r16r34 | A2BKB | |
| t1946 | 1 | 1 | r09r34r13r13r17r34r16r34 | A2BEEMBKB | |
| t1996 | 1 | 1 | r08r16r02r16r34r34r34r16r34 | XKAKBBBKB | |
| t266 | 1 | 1 | r09r02r16r13r13r13r17r34r16r34 | A2AKEEEMBKB | |
| t2757 | 1 | 1 | r08r181r34 | X??B | |
| t2758 | 1 | 1 | r08r16r182r16r34r17r34r16r34 | XK??KBMBKB | |
| t282 | 1 | 1 | r09r02r16r34 | A2AKB | |
| t2988 | 1 | 1 | r09r08r16r13r17r34 | A2AKEMB | |
| t3031 | 1 | 1 | r09r02r16r13r13r16r34 | A2AKEEKB | |
| t330 | 2 | 2 | r09r02r16r34r34r17r34r16r34 | A2AKBBMBKB | |
| t362 | 13 | 13 | r09r34 | A2B | |
| t390 | 1 | 1 | r08r16r16r34 | XKKB | |
| t553 | 1 | 1 | r09r13r13r17r34r16r34 | A2EEMBKB | |
| t589 | 2 | 2 | r08r16r02r16r34r34r13r17r34r16r34 | TK | |
| t630 | 7 | 4 | r08r16r02r16r34r17r34r16r34 | XKAKBMBKB | |
| t779 | 1 | 1 | r08 | X | |
| CMRSA2 (n=674) | t002 | 495 | 381 | r26r23r17r34r17r20r17r12r17r16 | TJMBMDMGMK |
| t003 | 14 | 13 | r26r17r20r17r12r17r17r16 | TMDMGMMK | |
| t010 | 4 | 3 | r26r17r34r17r20r17r12r17r16 | TMBMDMGMK | |
| t014 | 4 | 4 | r26r17r20r17r12r17r17r17r16 | TMDMGMMMK | |
| t045 | 23 | 13 | r26r17r20r17r12r17r16 | TMDMGMK | |
| t062 | 7 | 4 | r26r23r17r12r17r16 | TJMGMK | |
| t067 | 11 | 9 | r26r23r17r34r17r20r17r12r17 | TJMBMDMGM | |
| t088 | 7 | 6 | r26r23r17r34r17r20r17r12r12r17r16 | TJMBMDMGGMK | |
| t105 | 3 | 3 | r26r23r17r34r17r20r17r17r16 | TJMBMDMMK | |
| t1080 | 1 | 1 | r26r23r17r34r17r20r17r34r17r16 | TJMBMDMBMK | |
| t111 | 1 | 1 | r26r23r17r16 | TJMK | |
| t1154 | 1 | 1 | r26r20r17r12r17r16 | TDMGMK | |
| t1265 | 1 | 1 | r26r23r17r34r17r20r17r12r12r12r16 | TJMBMDMGGGK | |
| t1781 | 2 | 2 | r26r16r16 | TKK | |
| t179 | 2 | 2 | r26r23r17r34r17r20r17r12r12r16 | TJMBMDMGGK | |
| t1791 | 1 | 1 | r26r23r17r34r17r20r17r20r17r12r17r16 | TJMBMDMDMGMK | |
| t2066 | 1 | 1 | r26r23r17r34r17r20r17r12r17r12r17r16 | TJMBMDMGMGMK | |
| t214 | 2 | 2 | r26r23r17r34r17r20r17r12r17r16r16 | TJMBMDMGMKK | |
| t2212 | 2 | 2 | r26r23r17r34r22r17r12r17r16 | TJMBLMGMK | |
| t2235 | 5 | 5 | r26r23 | TJ | |
| t2302 | 2 | 2 | r26r23r17r34 | TJMB | |
| t2358 | 1 | 1 | r26r23r17r34r17r20r17r12r17r20r17r12r17r16 | TJMBMDMGMDMGMK | |
| t242 | 29 | 28 | r26r23r17r13r17r20r17r12r17r16 | TJMEMDMGMK | |
| t2528 | 2 | 2 | r26r23r17r34r12r12r12r16 | TJMBGGGK | |
| t306 | 1 | 1 | r26r23r17r34r17r20r17r12r17r17r16 | TJMBMDMGMMK | |
| t311 | 21 | 19 | r26r23r17r34r20r17r12r17r16 | TJMBDMGMK | |
| CMRSA2 (n=674) | t450 | 1 | 1 | r26r23r17r34r16 | TJMBK |
| t539 | 15 | 11 | r26r23r17r34r17r12r17r16 | TJMBMGMK | |
| t548 | 6 | 6 | r26r23r17r34r17r20r17r12r16 | TJMBMDMGK | |
| t586 | 2 | 2 | r26r16 | TK | |
| t601 | 1 | 1 | r26r23r17r34r34r17r20r17r12r17r16 | TJMBBMDMGMK | |
| t640 | 1 | 1 | r26r23r17r12r16 | TJMGK | |
| t653 | 2 | 2 | r26r17r12r17r16 | TMGMK | |
| t668 | 1 | 1 | r26r23r17r34r17r20r17r16 | TJMBMDMK | |
| t688 | 1 | 1 | r26r23r17r34r17r16 | TJMBMK | |
| t854 | 1 | 1 | r26r23r17r34r17r20r17r12r16r16 | TJMBMDMGKK | |
| t954 | 1 | 1 | r26r23r17r34r17r17r16 | TJMBMMK | |
| CMRSA3 (n=17) | t030* | 1 | 1 | r15r12r16r02r24r24 | WGKAQQ |
| t037* | 15 | 13 | r15r12r16r02r25r17r24 | WGKAOMQ | |
| t138 | 1 | 1 | r08r16r02r25r17r24 | XKAOMQ | |
| CMRSA4 (n=116) | t007 | 3 | 1 | r15r12r16r16r16r16r02r25r17 | WGKKKKAOM |
| t012 | 38 | 25 | r15r12r16r02r16r02r25r17r24r24 | WGKAKAOMQQ | |
| t018 | 35 | 25 | r15r12r16r02r16r02r25r17r24r24r24 | WGKAKAOMQQQ | |
| t019 | 15 | 8 | r08r16r02r16r02r25r17r24 | XKAKAOMQ | |
| t021 | 7 | 6 | r15r12r16r02r16r02r25r17r24 | WGKAKAOMQ | |
| t037* | 1 | 1 | r15r12r16r02r25r17r24 | WGKAOMQ | |
| t122 | 1 | 1 | r08r16r02r16r02r25r17r24r24 | XKAKAOMQQ | |
| t238 | 1 | 1 | r15r21r12r16r02r16r02r25r17r24r24 | WFGKAKAOMQQ | |
| t253 | 4 | 4 | r15r12r16r02r16r02r25r17r24r24r24r24 | WGKAKAOMQQQQ | |
| t275* | 1 | 1 | r15r12r16r02r25r17r24r24 | WGKAOMQQ | |
| t318 | 3 | 2 | r15r12r16r16r02r16r02r25r17r24 | WGKKAKAOMQ | |
| t323 | 4 | 3 | r15r12r16r02r16r34r17r24r24r24 | WGKAKBMQQQ | |
| t338 | 2 | 1 | r15r21r16r02r25r17r24 | WFKAOMQ | |
| t638 | 1 | 1 | r15r12r16r02r17 | WGKAM | |
| CMRSA5 (n=50) | t008* | 2 | 2 | r11r19r12r21r17r34r24r34r22r25 | YHGFMBQBLO |
| t051 | 1 | 1 | r11r19r21r12r21r17r34r24r34r22r25 | YHFGFMBQBLO | |
| t064 | 37 | 27 | r11r19r12r05r17r34r24r34r22r25 | YHGCMBQBLO | |
| t068 | 1 | 1 | r11r19r19r12r21r17r34r24r34r22r25 | YHHGFMBQBLO | |
| t1171 | 1 | 1 | r11r19r12r17r34r24r34r22r25 | YHGMBQBLO | |
| t190 | 2 | 2 | r11r17r34r24r34r22r25 | YMBQBLO | |
| t451 | 4 | 3 | r11r12r05r17r34r24r34r22r25 | YGCMBQBLO | |
| t460 | 1 | 1 | r11r19r21r17r34r24r24r34r22r25 | YHFMBQQBLO | |
| t951 | 1 | 1 | r11r10r05r17r34r24r34r22r25 | YC2CMBQBLO | |
| CMRSA6 (n=92) | t030* | 1 | 1 | r15r12r16r02r24r24 | WGKAQQ |
| t037* | 87 | 47 | r15r12r16r02r25r17r24 | WGKAOMQ | |
| t074 | 1 | 1 | r15r21r12r16r02r25r17r24 | WFGKAOMQ | |
| t129 | 1 | 1 | r15r12r24 | WGQ | |
| t275* | 1 | 1 | r15r12r16r02r25r17r24r24 | WGKAOMQQ | |
| t388 | 1 | 1 | r15r12r16r02r25r24 | WGKAOQ | |
| CMRSA7 (n=66) | t127 | 5 | 5 | r07r23r21r16r34r33r13 | UJFKBPE |
| t1274 | 1 | 1 | r07r23r21r16r16r33r21r16r33r21r16r33r13 | UJFKKPFKPFKPE | |
| t128 | 50 | 21 | r07r23r23r21r16r34r33r13 | UJJFKBPE | |
| t1508 | 1 | 1 | r15r16r34r33r13 | WKBPE | |
| t175 | 7 | 6 | r07r23r21r16r16r33r21r16r33r13 | UJFKKPFKPE | |
| t1784 | 1 | 1 | r07r34r33r13 | UBPE | |
| t2207 | 1 | 1 | r07r33r13 | UPE | |
| CMRSA7 (n=66) | t2593 | 1 | 1 | r07r23r21r34r33r13 | UJFBPE |
| t555 | 1 | 1 | r07r23r23r23r21r16r34r33r13 | UJJJFKBPE | |
| CMRSA8 (n=34) | t005 | 1 | 1 | r26r23r13r23r31r05r17r25r17r25r16r28 | TJEJNCMOMOKR |
| t020 | 1 | 1 | r26r23r31r29r17r31r29r17r25r17r25r16r28 | TJNF2MNF2MOMOKR | |
| t022 | 8 | 7 | r26r23r13r23r31r29r17r31r29r17r25r17r25r16r28 | TJEJNF2MNF2MOMOKR | |
| t032 | 17 | 13 | r26r23r23r13r23r31r29r17r31r29r17r25r17r25r16r28 | TJJEJNF2MNF2MOMOKR | |
| t1465 | 1 | 1 | r26r23r23r13r23r31r29r17r31r29r17r24r25r17r25r16r28 | TJJEJNF2MNF2MQOMOKR | |
| t2618 | 1 | 1 | r26r23r13r23r31r05r17r25r17r25r17r25r16r28 | TJEJNCMOMOMOKR | |
| t2818 | 1 | 1 | r26r23r23r13r23r31r29r17r31r29r17r25r17r24r25r16r28 | TJJEJNF2MNF2MOMQOKR | |
| t515 | 1 | 1 | r26r23r23r13r23r31r29r17r31r29r17r25r16r16r28 | TJJEJNF2MNF2MOKKR | |
| t578 | 2 | 2 | r26r23r23r13r23r31r29r17r31r29r17r25r17r25r28 | TJJEJNF2MNF2MOMOR | |
| t891 | 1 | 1 | r26r23r13r23r31r05r17r25r17r25r28 | TJEJNCMOMOR | |
| CMRSA9 (n=58) | t008* | 57 | 35 | r11r19r12r21r17r34r24r34r22r25 | YHGFMBQBLO |
| t955 | 1 | 1 | r11r19r12r21r17r34r24r34r22r33r25 | YHGFMBQBLPO | |
| CMRSA10 (n=198) | t008* | 186 | 37 | r11r19r12r21r17r34r24r34r22r25 | YHGFMBQBLO |
| t024 | 4 | 1 | r11r12r21r17r34r24r34r22r25 | YGFMBQBLO | |
| t068 | 1 | 1 | r11r19r19r12r21r17r34r24r34r22r25 | YHHGFMBQBLO | |
| t1705 | 1 | 1 | r11r34r24r34r22r25 | YBQBLO | |
| t1767 | 1 | 1 | r11r19r12r21r17r34r24r24r34r22r25 | YHGFMBQQBLO | |
| t2067 | 1 | 1 | r11r19r12r21r66r34r24r34r22r25 | YHGFF4BQBLO | |
| t3023 | 2 | 1 | r11r19r12r197r17r34r24r34r22r25r25 | YHG??MBQBLOO | |
| t3135 | 1 | 1 | r11r19r34r24r34r24r34r22r25 | YHBQBQBLO | |
| t3154 | 1 | 1 | r11r19r12r21r17r34r24r05r25 | YHGFMBQCO | |
| t351 | 1 | 1 | r11r19r12r21r22r25 | YHGFLO | |
| t574 | 2 | 1 | r11r19r12r12r34r24r34r22r25 | YHGGBQBLO | |
| t723 | 1 | 1 | r11r19r12r34r22r25 | YHGBLO | |
| t818 | 1 | 1 | r11r19r12r21r17r34 | YHGFMB |
*
Refer to discussion section for assignment of spa types t008, t030, t037 and t275 to a CMRSA epidemic type