Fig. 2.

Different kinetics of thrombin-induced transient cytosolic Ca²⁺ concentration ([Ca²⁺]_cyt) increases in PASMC and PAEC. A: representative data depict the transient increase in [Ca²⁺]_cyt induced by 10 nM thrombin in PASMC (top) and PAEC (bottom); [Ca²⁺]_cyt elevations are described as the F/F₀ ratio of fura 2 fluorescence. B: summarized data showing the amplitude (left) and duration (right) of thrombin-induced [Ca²⁺]_cyt transients in PASMC (black bars, n = 11) and PAEC (gray bars, n = 18–19). *P < 0.05, ***P < 0.001 vs. PASMC.