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. 2008 Oct 10;295(6):L1056–L1065. doi: 10.1152/ajplung.90329.2008

Fig. 5.

Fig. 5.

A: the effect of ventilation with 7 (n = 4) or 20 ml/kg VT for 4 h without (n = 5) and with (n = 5) ODQ pretreatment (10 mg/kg ip) on lung Evans blue dye albumin (EBD) content in anesthetized C57BL/6 mice. Values are means ± SE. *P < 0.005 vs. 7 ml/kg VT and ODQ-treated 20 ml/kg VT. B: the effect of ventilation with 7 or 20 ml/kg VT (n = 5) for 4 h on wet-to-dry weight ratio (WW/DW) compared with sham-ventilated mice (n = 10). A separate group of 20 ml/kg VT lungs (n = 5) was pretreated with ODQ (10 mg/kg ip). Values are means ± SE. *P < 0.001. C: the effect of increasing ODQ dose in anesthetized mice on lung homogenate nitric oxide synthase (NOS) activity (n = 3).