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. Author manuscript; available in PMC: 2009 Aug 1.
Published in final edited form as: Bone. 2008 Apr 13;43(2):264–273. doi: 10.1016/j.bone.2008.03.024

Table 4.

μCT analysis of cortical bone parameters in femur (mean ± SEM). N = 7-8 mice per group

Wild type Haploinsufficient Null
Parameter 10 wk 14 wk vehicle 14 wk PTH 10 wk 14 wk vehicle 14 wk PTH 10 wk 14 wk vehicle 14 wk PTH
Periosteal area (mm2) 1.65 ± 0.06 1.65 ± 0.23 1.70 ± 0.03 1.60 ± 0.04 1.60 ± 0.31 1.75 ± 0.03 b 1.46 ± 0.04 1.47 ± 0.03 c 1.60 ± 0.02 b
Endosteal area (mm2) 0.88 ± 0.03 0.85 ± 0.02 0.81 ± 0.02 0.85 ± 0.03 0.79 ± 0.02 0.84 ± 0.02 b 0.71 ± 0.03 0.68 ± 0.02 c 0.73 ± 0.03 b
Bone area (mm2) 0.68 ± 0.03 0.76 ± 0.01 a 0.82 ± 0.02 b 0.68 ± 0.02 0.76 ± 0.02 a 0.86 ± 0.02 b 0.68 ± 0.01 0.73 ± 0.01 c 0.82 ± 0.02 b
a

significantly different from corresponding 10 week, p ≤ 0.04

b

significantly different from corresponding vehicle treated, p ≤ 0.02;

c

significantly different from vehicle treated wild type, p ≤ 0.02