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Annexin A2 heterotetramer (AnxA2t)-mediated junction formation [modified from Lambert et al. (54)]. AnxA2-p11 complex (AnxA2t) forms a symmetrical bridge between 2 lipid bilayers (only 1 of the 2 participating lipid bilayers is shown at right). The 2 annexin A2 (AnxA2) subunits, each binding to a separate bilayer, are, in turn, linked by a p11 dimer. [Modified from Lee et al. (55).]
