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Growth curves. Claudin-16 (CLDN16) knockdown (KD) mice are significantly smaller compared with their counterpart wild-type (WT) litters already at the weaning age. A: weight development for each genotype and sex in the first 7 wk after birth. B: comparison between genotype and sex at 2 and 7 wk of age. Data are means ± SE; n = 5–11/group. *P < 0.05, WT vs. KD; +P < 0.05, female vs. male.
