Table I.
Effects of curcumin, 4MC, and 4HC on the viability of urothelial cells cultured on Matrigel, SISgel, or plastic
| IC50 (μM) | |||
|---|---|---|---|
| Curcumin | MATRI | SIS | PLASTIC |
| UROTSA | 64.2 ± 1.1 | 10.3 ± 1.4 | 3.9 ± 1.2 |
| HUC | >400 | 24.6 ± 1.1 | 7.8 ± 1.1 |
| RT4 | 243.4 ± 1.1 | 87.0 ± 1.1 | 3.5 ± 1.3 |
| 5637 | 234.4 ± 1.1 | 38.2 ± 1.1 | 10.5 ± 1 |
| J82 | 115.5 ± 1 | 22.9 ± 1.3 | 20.5 ± 1.1 |
| TCCSup | 171.6 ± 1 | 46.0 ± 1.1 | 18.3 ± 1.1 |
| 4MC | MATRI | SIS | PLASTIC |
| UROTSA | 237.1 ± 1 | 9.1 ± 1.4 | 1.2 ± 2.6 |
| HUC | >400 | 7.9 ± 1.4 | 7.3 ± 1 |
| RT4 | >400 | 134.4 ± 1.1 | 20.8 ± 1.2 |
| 5637 | >400 | 41.5 ± 1.1 | 10.5 ± 1.8 |
| J82 | >400 | 30.4 ± 1.2 | 21.2 ± 1.7 |
| TCCSup | >400 | 85.7 ± 1.1 | 15.3 ± 1.2 |
| 4HC | MATRI | SIS | PLASTIC |
| UROTSA | 84.3 ± 1.1 | 8.3 ± 1.4 | 6.9 ± 1.1 |
| HUC | 171.2 ± 1.1 | 2.8 ± 2 | 1.6 ± 1.4 |
| RT4 | 102.5 ± 1 | 63.6 ± 1.1 | 10.6 ± 1 |
| 5637 | 106.8 ± 1.1 | 29.1 ± 1.1 | 7.6 ± 1 |
| J82 | 155.3 ± 1 | 22.4 ± 1.2 | 12.8 ± 1.1 |
| TCCSup | 164.7 ± 1.1 | 46.5 ± 1 | 21.4 ± 1.2 |