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Op/op mice lack SIGN-R1 expression on marginal zone macrophages. Spleen sections from wild type C57BL/6 (A) and op/op mice (B) were examined for marginal zone macrophage receptor expression by immunofluorescent staining for CD169 (green), MARCO (red), and SIGN-R1 (blue). Imaging conditions for each fluorescent channel were identical for each sample.
