Table 1.
Comparison of mutation rates in Cse4p-binding and other genomic noncoding regions in C. albicans and C. dubliniensis
| Cse4p-binding (%) | Cse4p-binding (shuffled) (%) | Pericentric (%) | Intergenic (%) | |
|---|---|---|---|---|
| Total bases | 26,836 | 26,836 | 40,280 | 593,782 |
| Aligned (DIALIGN2) | 12,440 (46) | 11,650 (43) | 27,684 (68) | 530,847 (89) |
| Mutated (DIALIGN2) | 7,624 (61) | 7,201 (62) | 10,229 (36) | 154,473 (29) |
| Aligned (Sigma) | 0 | 0 | 15,015 (37) | 334,363 (56) |
| Mutated (Sigma) | 0 | 0 | 3,323 (22) | 57,548 (17) |
The fraction of bases aligned by Sigma and DIALIGN2 and the mutation rates within the aligned regions, for Cse4p-binding regions, pericentric regions, and intergenic regions are shown. Also shown, as a null hypothesis, are numbers for ″shuffled″ Cse4p-binding regions, where regions from different nonorthologous chromosomes were aligned.