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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Genes Brain Behav. 2008 Sep 17;7(8):933–942. doi: 10.1111/j.1601-183X.2008.00432.x

Figure 7. Acquisition, expression and extinction of conditioned fear in TIP39-KO mice.

Figure 7

TIP39-KO mice froze more than WT controls during fear conditioning (a), during the tone test (b) and during the context test (c) (WT, n = 18; KO, n = 17). In an extinction test, TIP39-KO mice froze more during conditioning (d, first panel) and at the beginning of the tone test (d-second panel) than WT controls. Rates of within-session extinction (d, second panel) and extinction recall (d, third panel) were not different between genotypes (WT, n = 8; KO, n = 10). Shock sensitivity did not differ significantly between genotypes at any intensity measured (e) (n = 8/genotype). WT, open bars or squares; KO, solid bars or squares. Data are mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001.